VEGF-C-expressing TAMs rewire the metastatic fate of breast cancer cells.

Banerjee K, Kerzel T, Bekkhus T, Ferreira de Souza S, Wallmann T, Wallerius M, Landwehr LS, Agardy DA, Schauer N, Malmerfeldt A, Bergh J, Bartish M, Hartman J, Östman A, Squadrito ML and Rolny C. Cell Reports. 2023 Dec 1;42(12):113507. doi: 10.1016/j.celrep.2023.113507 

MNK2 governs the macrophage antiinflammatory phenotype.

Bartish M, Tong D, Pan Y, Wallerius M, Liu H, Ristau J, de Souza Ferreira S, Wallmann T, van Hoef V, Masvidal L, Kerzel T, Joly AL, Goncalves C, Preston SEJ, Ebrahimian T, Seitz C, Bergh J, Pietras K, Lehoux S, Naldini L, Andersson J, Squadrito ML, Del Rincón SV, Larsson O and Rolny C. Proc Natl Acad Sci U S A. 2020 Nov 3;117(44):27556-27565. doi: 10.1073/pnas.1920377117. Epub 2020 Oct 19.PMID: 33077599’’

Microglia Induce PDGFRB Expression in Glioma Cells to Enhance Their Migratory Capacity.

Wallmann T, Zhang XM, Wallerius M, Bolin S, Joly AL, Sobocki C, Leiss L, Jiang Y, Bergh J, Holland EC, Enger PØ, Andersson J, Swartling FJ, Miletic H, Uhrbom L, Harris RA

and  Rolny C.

iScience. 2018 Nov 30;9:71-83. doi: 10.1016/j.isci.2018.10.011. Epub 2018 Oct 16.

Guidance Molecule SEMA3A Restricts Tumor Growth by Differentially Regulating the Proliferation of Tumor-Associated Macrophages.

Wallerius M, Wallmann T, Bartish M, Östling J, Mezheyeuski A, Tobin NP, Nygren E, Pangigadde P, Pellegrini P, Squadrito ML, Pontén F, Hartman J, Bergh J, De Milito A, De Palma M, Östman A, Andersson J, and Rolny C.

Cancer Res. 2016 Jun 1;76(11):3166-78. doi: 10.1158/0008-5472.CAN-15-2596. Epub 2016 Apr 6.

Systemic and targeted delivery of semaphorin 3A inhibits tumor angiogenesis and progression in mouse tumor models.

Casazza A, Fu X, Johansson I, Capparuccia L, Andersson F, Giustacchini A, Squadrito ML, Venneri MA, Mazzone M, Larsson E, Carmeliet P, De Palma M, Naldini L, Tamagnone L and Rolny C. Arterioscler Thromb Vasc Biol. 2011 Apr;31(4):741-9. doi: 10.1161/ATVBAHA.110.211920. Epub 2011 Jan 4.PMID: 21205984 

HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF.

Rolny C, Mazzone M, Tugues S, Laoui D, Johansson I, Coulon C, Squadrito ML, Segura I, Li X, Knevels E, Costa S, Vinckier S, Dresselaer T, Åkerud P, De Mol M, Salomäki H, Phillipson M, Wyns S, Larsson E, Buysschaert I, Botling J, Himmelreich U, Van Ginderachter JA, De Palma M, Dewerchin M, Claesson-Welsh L, Carmeliet P.

Cancer Cell. 2011 Jan 18;19(1):31-44. doi: 10.1016/j.ccr.2010.11.009. Epub 2011 Jan 6.